The No. 9 Notre Dame Fighting Irish (7-2) hit the road to meet the No. 23 Pittsburgh Panthers (7-2) at Acrisure Stadium on Saturday, November 15, 2025.
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Notre Dame vs. Pittsburgh Matchup Info
- Game date: Saturday, November 15, 2025
- Game time: 12 p.m. ET
- Location: Pittsburgh, Pennsylvania
- Venue: Acrisure Stadium
- TV channel: ABC
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Notre Dame vs. Pittsburgh Odds and Prediction
- Spread favorite: Fighting Irish (-12.5)
- Moneyline: Fighting Irish (-455), Panthers (+351)
- Total: 54.5 points
- Pick ATS: Pittsburgh (+12.5)
- Pick OU: Over (54.5)
- Prediction: Notre Dame 32, Pittsburgh 27
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Notre Dame vs. Pittsburgh Betting Records and Insights
- Notre Dame has covered four times in nine chances against the spread this season.
- Pittsburgh has covered seven times in nine matchups with a spread this year.
- The Fighting Irish have an ATS record of 3-2 when playing as at least 12.5-point favorites this season.
- In Notre Dame's nine games this season, the combined scoring has gone over the point total five times.
- Pittsburgh and its opponent have combined to go over the point total six out of nine times this season.